Journal article
The ultrastructure of taeniid cestode oncospheres and localization of host-protective antigens
A Jabbar, Z Swiderski, D Mlocicki, I Beveridge, MW Lightowlers
Parasitology | Published : 2010
Abstract
Taeniid eggs contain an infective larval form of the parasite, known as the oncosphere, which has been found to be highly susceptible to attack by the host's immune system and this fact has been exploited in the development of highly effective vaccines. Relatively little is known about the structure of taeniid oncospheres and the localization of host-protective antigens within or on the oncosphere. Here, we briefly review the current state of knowledge of the structure of the oncosphere and present preliminary data on the localization of a host-protective antigen within the oncospheres of Taenia ovis. The precise localization of the antigens, in the context of a detailed knowledge of the ult..
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Awarded by National Health and Medical Research Council
Funding Acknowledgements
The authors wish to acknowledge the expert technical assistance of the late Mrs Josie Wilson as well as Mr Paul Benham and Dr Simon Crawford. Funding from National Health and Medical Research Council (grant 350279) is acknowledged.